1、教育经历
2016/09 – 2021/06，中国科学院上海有机化学研究所，理学博士，导师: 黄正研究员
2012/09 – 2016/06，中国科学技术大学，理学学士，导师: 徐允河教授
2、工作经历
2026/06 – 至今 雷竞技raybat下载 教授
2021/11 – 2026/05 University of Wisconsin-Madison 博士后, 合作导师: Daniel J. Weix
2021/06 – 2021/10 中国科学院上海有机化学研究所 研究助理
3、学术荣誉
2025，国家高层次青年人才（海外）
（1）新颖金属有机中间体的分离表征
（2）基于基元反应创新的不对称反应开发
（3）生物活性分子的立体化修饰及活性评价
科研项目
2025 国家高层次青年人才（海外）
2026 雷竞技raybat下载兴药领军学者A类
学术成果
（1）镍催化脱羰用于C(sp³)-C(sp³)交叉偶联及其立体选择性控制（Nature 2026, 655, 1187；Science 2024, 385, 1331）
（2）铱催化乙醇脱氢用于不饱和烃的选择性转移氢化（J. Am. Chem. Soc. 2021, 143, 4824；Nat. Catal. 2019, 2, 529）
（3）金属催化新型硅化方法开发（J. Am. Chem. Soc. 2022, 144, 20903；Chem. Commun. 2016, 52, 5609）
1.Huang, Z.†; Wu, T.†; Yuan, Z.; Meng, C.; Garman, L. C.; Guzei, I. A.; Wu, B.; Weix, D. J., Stereoretentive decarbonylative C(sp3)–C(sp3) cross-coupling. Nature 2026, 655, 1187-1194.
2.Huang, Z., Akana M. E., Sanders K. M., and Weix D. J. A Decarbonylative Approach to Alkylnickel Intermediates and C(sp3)-C(sp3) Bond Formation. Science 2024, 385, 1331-1337.
3.Qin, C.†; Huang, Z.†; Wu, S.-B.†; Li, Z.; Yang, Y.; Xu, S.; Zhang, X.; Liu, G.; Wu, Y.-D.; Chung, L. W.; Huang, Z. Breaking Conventional Site Selectivity in C–H Bond Activation: Selective sp3 versus sp2 Silylation by a Pincer-Based Pocket. J. Am. Chem. Soc. 2022, 144, 20903-20914.
4.Huang, Z.†; Wang, Y.†; Leng, X.; Huang, Z. An Amine-Assisted Ionic Monohydride Mechanism Enables Selective Alkyne cis-Semihydrogenation with Ethanol: From Elementary Steps to Catalysis. J. Am. Chem. Soc. 2021, 143, 4824-4836.
5.Wang, Y.†; Huang, Z.†; Huang, Z. Catalyst as Colour Indicator for Endpoint Detection to Enable Selective Alkyne trans-Hydrogenation with Ethanol. Nat. Catal. 2019, 2, 529-536.
6.Huang, Z.; Ding, R.; Wang, P.; Xu, Y.-H.; Loh, T.-P. "Palladium-Catalyzed Silylation Reaction Between Benzylic Halides and Silylboronate" Chem. Commun. 2016, 52, 5609-5612.
7.Huang, F.†; Huang, Z.†; Liu, G.; Huang, Z. Iridium-Catalyzed Selective trans-Semihydrogenation of 1,3-Enynes with Ethanol: Access to (E,E)-1,4-Diarylbutadienes. Org. Lett. 2022, 24, 5486-5490.
8.Wang, J.; Ehehalt, L. E.; Huang, Z.; Beleh, O. M.; Guzei, I. A.; Weix, D. J. Formation of C(sp2)–C(sp3) Bonds Instead of Amide C–N Bonds from Carboxylic Acid and Amine Substrate Pools by Decarbonylative Cross-Electrophile Coupling. J. Am. Chem. Soc. 2023, 145, 9951-9958.
9.Wang, Y.; Huang, Z.; Liu, G.; Huang, Z. A New Paradigm in Pincer Iridium Chemistry: PCN Complexes for (De)Hydrogenation Catalysis and Beyond. Acc. Chem. Res. 2022, 55, 2148-2161.
10.Qian, L.; Tang, X.; Huang, Z.; Wang, Y.; Liu, G.; Huang, Z. Chiral Iridium Complexes of Anionic NCP Pincer Ligand for Asymmetric Transfer Hydrogenation of 1,1-Diarylethenes with Ethanol. Org. Lett. 2021, 23, 8978-8983.
11.Wang, Y.; Qian, L.; Huang, Z.; Liu, G.; Huang, Z. Chin. J. Chem. 2020, 38, 837-841.
12.Wang, Y.; Huang, Z.; Leng, X.; Zhu, H.; Liu, G.; Huang, Z. Transfer Hydrogenation of Alkenes Using Ethanol Catalyzed by a NCP Pincer Iridium Complex: Scope and Mechanism. J. Am. Chem. Soc. 2018, 140, 4417-4429.
13.Ding, R.; Huang, Z.; Liu, Z.; Wang, T.; Xu, Y.; Loh, T.-P. Chem. Commun. 2016, 52, 5617-5620.
